联系方式

南京大学环境学院C520
电话：(025) 89680359
电子邮件：ecsxg@nju.edu.cn

主要研究方向

在有机污染化学研究方面，主要开展有机污染物生物降解、生物有效性调控及水环境归趋研究。在污染生态化学研究方面，主要研究污染物在水环境中的转化、生物富集、污染物生态毒性、生态风险评价及水环境基准等。

学 历

1982. 7 华东石油学院炼制系本科毕业
1985. 8 中国科学院环境化学研究所硕士研究生毕业
1999. 7 南京大学环境学院博士研究生毕业

研究经历

2003年至今：南京大学环境学院教授，博士生导师；
2013/6-2013/11，美国威斯康辛大学麦迪孙分校（The University of Wisconsin-Madison）土壤科学系高级访问学者
2006年起：南京大学环境科学研究所副所长
2000-2008年：南京大学环境化学教研室主任;
1999-2002年：南京大学环境学院副教授；
1989-1991年：加拿大不列颠哥伦比亚大学（The University of British Columbia）化学系访问学者;
1985-1999年：江苏省理化测试中心工程师、副研究员；

主持科研项目

1. 国家自然科学基金面上项目，天然水体中自然光与过氧化物酶协同降解消毒剂类污染物的机理研究，2016/01-2019/12，主持
2. 国家自然科学基金面上项目，有机磷阻燃剂的鱼体代谢过程及其毒性效应的结构-活性关系，2014/01-2017/12，主持
3. 环保部环保公益性行业科研专项，化学工业废水处理污泥污染特征与污染风险控制研究，2015/04-2018/04，参加
4. 国家“973”项目，持久性有机污染物的环境行为、毒性效应与控制技术原理，课题4“POPs污染物的生物转移、累积与放大”，2009.1-2013.12，参加
5. 环保部环保公益性行业科研专项，兽药污染的健康风险评估与风险管理技术研究，2011.1-2014.1，参加
6.国家自然科学基金项目，多溴联苯醚肝脏代谢机理的模拟研究 ，2010.1-2012.12，主持
7. 国家“863”重大项目，重大环境污染事件应急技术系统研究开发与应用示范”课题“重大环境污染事件风险场预警技术， 2007.12-2012.8，主持
8. 国家“十一五”国家水体污染控制与治理科技重大专项课题，流域水环境质量基准与标准体系研究课题，子课题“流域水生生物毒理学效应基准指标与基准阈值”，2008.1-2011.12，参加
9. 国家自然科学基金项目，白腐菌降解多溴二苯醚的机理研究，2007.1-2009.12，主持
10.江苏省社会发展项目，大气污染对六朝石刻的影响及保护对策研究，2006.1-2008.12，主持
11.国家自然科学基金项目，环糊精促进难降解有机污染物生物降解研究，2001.1-2003.12，主持

奖励及学术兼职

1.新型污染物的环境过程机制及其结构-活性关系的研究，教育部高等学校科学研究优秀成果奖-自然科学奖, 二等奖，2012年12 月
2.有毒有机物结构与作用机理的研究，教育部自然科学奖，二等奖，2002年12月
3.《环境化学》编委
4.《生态与农村环境学报》编委
5.中国环境科学学会持久性有机污染物专业委员会委员
6.中国毒理学会环境与生态毒理学专业委员会委员
7.江苏科技大学兼职教授

近期发表的论文

1. Yang, Yun; Li, Jianhua; Lu, Kun; Shi, Huanhuan; Gao, Shixiang*, Transformation of 17alpha-ethinylestradiol by simultaneous photo-enzymatic process in Humic water. Chemosphere, 178:432-438, 2017
2. Jianbiao Peng, Jie Xue, Jianhua Li, Zhongkun Du, Zunyao Wang, Shixiang Gao*, Catalytic effect of low concentration carboxylated multi-walled carbon nanotubes on the oxidation of disinfectants with Cl-substituted structure by a Fenton-like system, Chemical Engineering Journal, 321:325–334, 2017
3. Wang, Guowei; Chen, Hanyan; Du, Zhongkun; Li, Jianhua; Wang, Zunyao; Gao, Shixiang*， In vivo metabolism of organophosphate flame retardants and distribution of their main metabolites in adult zebrafish. The Science of the total environment，590-591:50-59，2017
4. Jianhua Li, Ya Zhang, Qingguo Huang, Huanhuan Shi, Yun Yang, Shixiang Gao?, Liang Mao, Xi Yang；Degradation of organic pollutants mediated by extracellularperoxidase in simulated sunlit humic waters: A case study with17beta-estradiol，Journal of Hazardous Materials, 331：123–131，2017
5. Jianhua Li, Ya Zhang, Jianbiao Peng, Xinan Wu, Shixiang Gao*, Liang Mao，The effect of dissolved organic matter on soybean peroxidase-mediated removal of triclosan in water，Chemosphere, 172:399-407, 2017
6. Feng, Yiping; Lu, Kun; Gao, Shixiang*; Mao, Liang*, The fate and transformation of tetrabromobisphenol A in natural waters, mediated by oxidoreductase enzymes. Environmental science. Processes & impacts, 19(4): 596-604，2017
7. Lu, Kun; Dong, Shipeng; Petersen, Elijah J; Niu, Junfeng; Chang, Xiaofeng; Wang, Peng; Lin, Sijie; Gao, Shixiang; Mao, Liang*，Biological Uptake, Distribution, and Depuration of Radio-Labeled Graphene in Adult Zebrafish: Effects of Graphene Size and Natural Organic Matter. ACS nano, 11(3) :2872-2885, 2017
8. Wang, GW; Du, ZK; Chen, HY; Su, Y; Gao, SX?; Mao, L；Tissue-Specific Accumulation, Depuration, and Transformation of Triphenyl Phosphate (TPHP) in Adult Zebrafish (Danio rerio)，ENVIRONMENTAL SCIENCE & TECHNOLOGY，50（24）: 13555-13564，2016
9. Peng, Jianbiao; Shi, Huanhuan; Li, Jianhua；Wang, LH；Wang, ZY; Gao, SX*；Bicarbonate enhanced removal of triclosan by copper(II) catalyzed Fenton-like reaction in aqueous solution，CHEMICAL ENGINEERING JOURNAL，306: 484-491，2016
10. Wang, Pingping; Du, Zhongkun; Gao, Shixiang*; Zhang, XW*; Giesy, JP；Impairment of reproduction of adult zebrafish (Danio rerio) by binary mixtures of environmentally relevant concentrations of triclocarban and inorganic mercury，ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY，134: 124-132，2016
11. Shi, HH; Peng, JB; Li, JH; Mao, L; Wang, ZY; Gao, SX*; Laccase-catalyzed removal of the antimicrobials chlorophene and dichlorophen from water: Reaction kinetics, pathway and toxicity evaluation，JOURNAL OF HAZARDOUS MATERIALS，317: 81-89，2016
12. Dong, SP; Xiao, HF; Huang, QG; Zhang, J; Mao, L*; Gao, SX*，Graphene Facilitated Removal of Labetalol in Laccase-ABTS System: Reaction Efficiency, Pathways and Mechanism，SCIENTIFIC REPORTS， 6: 21396，DOI: 10.1038/srep21396，2016
13. Du ZK, Zhang Y, Wang GW, Peng JB, Wang ZY, Gao SX*. TPhP exposure disturbs carbohydrate metabolism, lipid metabolism, and the DNA damage repair system in zebrafish liver. Scientific Reports. 6:21827，DOI: 10.1038/srep21827，2016.
14. Li JH, Zhang Y, Du ZK, Peng JB, Mao L, Gao SX*. Biotransformation of OH-PBDEs by pig liver microsomes: Investigating kinetics, identifying metabolites, and examining the role of different CYP isoforms. Chemosphere. 148: 354-360, 2016.
15. Li JH, Peng JB, Zhang Y, Ji YF, Shi HH, Mao L, Gao SX*. Removal of triclosan via peroxidases-mediated reactions in water: Reaction kinetics, products and detoxification. Journal of Hazardous Materials. 310: 152–160, 2016.
16. Peng JB, Li JH, Shi HH, Wang ZY, Gao SX*. Oxidation of disinfectants with Cl-substituted structure by a Fenton-like system Cu2+/H2O2 and analysis on their structure-reactivity relationship, Environ. Sci. Pol. Res. 23:1898–1904, 2016
17. Lu, Kun; Huang, Qingguo; Xia, Tian; Chang, Xiaofeng; Wang, Peng; Gao, Shixiang; Mao, Liang*, The potential ecological risk of multiwall carbon nanotubes was modified by the radicals resulted from peroxidase-mediated tetrabromobisphenol A reactions, ENVIRONMENTAL POLLUTION, 220: 264-273(A), 2016
18. Kan Haifeng; Zhao Fuzheng; Zhang Xu-Xiang*; Ren Hongqiang; Gao Shixiang*， Correlations of Gut Microbial Community Shift with Hepatic Damage and Growth Inhibition of Carassius auratus Induced by Pentachlorophenol Exposure，ENVIRONMENTAL SCIENCE & TECHNOLOGY，49（19）: 11894-11902，2015
19. Du Zhongkun; Wang Guowei; Gao Shixiang*; Wang Zunyao，Aryl organophosphate flame retardants induced cardiotoxicity during zebrafish embryogenesis: By disturbing expression of the transcriptional regulators，AQUATIC TOXICOLOGY，161（1）: 25-32，2015.
20. Feng YP; Lu K; Mao L*; Guo XK; Gao SX; Petersen EJ, Degradation of C-14-labeled few layer graphene via Fenton reaction: Reaction rates, characterization of reaction products, and potential ecological effects, WATER RESEARCH, 84: 49-57, 2015.
21. Dong S, Mao Liang *, Luo S, Zhou L, Feng Y, Gao S*. Comparison of lignin peroxidase and horseradish peroxidase for catalyzing the removal of nonylphenol from water. Environ. Sci. Pollut. Res., 21:2358-2366, 2014.
22. Wang Na; Yang Xiaohong; Jiao Shaojun; Zhang Jun; Ye Boping*; Gao Shixiang*; Sulfonamide-Resistant Bacteria and Their Resistance Genes in Soils Fertilized with Manures from Jiangsu Province, Southeastern China, PLOS ONE, 9(11): e112626, 2014
23. Wang Na; Guo Xinyan; Xu Jing; Kong Xiangji; Gao Shixiang*; Shan Zhengjun, Pollution characteristics and environmental risk assessment of typical veterinary antibiotics in livestock farms in Southeastern China, J.ENVIRON. SCI. HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES, 49(7): 468-479, 2014.
24. Feng YP, Colosi LM., Gao SX, Huang QG, Mao L* Transformation and Removal of Tetrabromobisphenol A from Water in the Presence of Natural Organic Matter via Laccase-Catalyzed Reactions: Reaction Rates, Products, and Pathways，Environ. Sci. Technol, 47 (2): 1001–1008, 2013.
25. Cheng J., Mao L., Zhao Z.G., Shen M.G., Zhang S.G., Huang Q.G., Gao S.X*., Bioaccumulation, depuration and biotransformation of 4,4’-dibromodiphenyl ether in crucian carp (Carassius auratus). Chemosphere，86：446–453 , 2012
26. Shen M., Cheng J., Wu R.H., Zhang S.H., Mao L., Gao S.X*., Metabolism of polybrominated diphenyl ethers and tetrabromobisphenol A by ?sh liver subcellular fractions in vitro. Aquat. Toxicol., 114–115:73-79, 2012
27. Jie Cheng, Mengnan Shen, Jianfeng Wu, Zhigang Zhao, Liang Mao and Shixiang Gao*， Distribution and Assessment of Heavy Metals in Surface Water and Sediments from Nanjing Chemical Industrial Park，Fresenius Environmental Bulletin，21（9）:2702-2710，2012
28. Shi JQ., Cheng J, Wang FY, Flamm A, Wang ZY, Yang X, Gao SX, Acute toxicity and n-octanol/water partition coefficients of substituted thiophenols: Determination and QSAR analysis, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 78:134-141, 2012
29. Han Chao; Geng Jinju; Xie Xianchuan; Wang Xiaorong; Ren Hongqiang; Gao Shixiang, Determination of Phosphite in a Eutrophic Freshwater Lake by Suppressed Conductivity Ion Chromatography, Environ. Sci. Technol., 46(19): 10667-10674, 2012
30. Zhao, Yanping; Gu, Xueyuan; Gao, Shixiang; Adsorption of tetracycline (TC) onto montmorillonite: Cations and humic acid effects, GEODERMA , (183): 12-18, 2012

鉴定成果

1.南京市大气气溶胶以有毒有机物的污染状况、化学表征与源识别研究，王连生，高士祥, 王格慧，黄鹂鸣，吴海锁，王荟，高松亭, 江苏省科技厅，2002.11.24 成果编号：鉴字[2002]第701号
2.常州怡康花园住宅小区土壤修复技术研究， 王连生，韩朔睽，高松亭，高士祥, 王炳坤，刘育民，俞国钢，高立生，江苏省科学技术委员会，1998.12.28 成果编号：苏科 鉴字[98]第582号
3.用化学和生物方法合成鬼臼毒素类化合物的研究，高士祥，丁家宜，鲜啓鸣，江苏省科学技术委员会，1997.7.20